Determining the Effect of Ultraviolet rays on the development of hydatid cyst in Mice

Abstract

The aim of this study was to evaluate the effect of ultraviolet rays on the development of hydatid cyst and to study the histopathological changes of hydrated cysts. The work was conducted at the Department of Biology, Faculty of Education.  The hydatid cyst were opened and the protoscoleces were exposed to different doses of ultraviolet rays irradiation (18000, 27000, 54000 and 81000 Erg /mm /sec) The viability of the protoscoleces was measured by staining with Eosin and they intraperitoneal inoculation in mice (Five for each dose) with a number of 400 protoscoleces each mice. Four weeks later, the mice were challenged with a dose of 2000 unexposed protoscoleces for each mouse.  The results of ultraviolet irradiation showed that there was difference in the establishment rate and the development of cysts inside the mice where the number was reduced with the irradiation doses compared to the control group which was not exposed to irradiation. Most of the cysts developed in the liver and peritoneal cavity. The effect of irradiation was obvious as the cysts were not well developed and small in size compared to the control groups.